Primary photochemical event in vision: proton translocation.
نویسندگان
چکیده
منابع مشابه
Primary photochemical event in vision: proton translocation.
Picosecond studies of rhodopsin in low-temperature glasses have been carried out in order to observe directly the risetime of prelumirhodopsin, the first intermediate in the visual pathway. Only at 20 K or below can the risetime of this intermediate be resolved and even at 4 K it is astoundingly rapid, about 36 psec. An examination of the Arrhenius dependence on temperature of the rate of forma...
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The energy-storage, the electronic-excitation energy-shift and the molecular rearrangements due to the primary photochemical event in rhodopsin are investigated using QM/MM(MO:MM) hybrid methods in conjunction with high-resolution structural data of bovine visual rhodopsin. It is assumed that the primary process involves 11-cis/all-trans isomerization of the retinyl chromophore within a time sc...
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The active transport of protons across the low dielectric barrier imposed by biological membranes is accomplished by a plethora of proteins that span the ca. 40 ~ of the phospholipid bilayer. The free energy derived from the proton electrochemical potential established by the translocation of these protons can subsequently be used to drive vital chemical reactions of the cell, such as ATP synth...
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The photoisomerization reaction dynamics of a retinal chromophore in the visual receptor rhodopsin was investigated by means of hybrid quantum mechanical/molecular mechanical (QM/MM) molecular dynamics (MD) simulations. The photoisomerization reaction of retinal constitutes the primary step of vision and is known as one of the fastest reactions in nature. To elucidate the molecular mechanism of...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1977
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.74.8.3119